Opuntiagomei is a common prickly pear near the Rio Grande River delta, but it may occur inland somewhat on the South Texas Plains.
O.gomei may form large shrubs 1 m tall and up to 3 m across. Major branches of this opuntia often rest upon the ground and other branches arise from them. Old, large cacti often contain dead material in the centers. Large cladodes may by 40 to 60 cm (or more) in diameter. The cactus spines are erect and divergent. The largish pads are often scalloped. The yellow spines are 2-4(5) cm long and there are often 2-4(5) spines per areole, which are stout, straight, and not curved. Glochids are abundant and prominent in this opuntia, up to 1 cm. The glochids may fill the entire areole as is the case with O.lindheimeri.
The flowers are yellow, but red flowers have been reported. The stigma is large and bright deep-green. The fruits are reddish purple.
Opuntia ‘Old Mexico’ is possibly a cultivar of O.gomei.